Who we’re: The Sinclair analysis group is a world chief within the understanding of why we age and the way to reverse it. Our lab has skilled over 100 individuals who will at all times stay a part of the prolonged Sinclair lab household. College students and postdocs who practice in our lab depart with a broad training within the newest applied sciences and approaches to science, together with abilities in management and entrepreneurship, happening to profitable careers in business and academia. Many alumni are professors in academia or leaders in business or enterprise capital. They’re inventors on patents and a few have based profitable firms out of the Sinclair lab or different labs. To this point, our lab members have had a hand within the formation of over 15 firms, together with Sirtris, Highlight, Iduna, Immetas, Genocea, Life Biosciences, Jumpstart Fertility, Continuum, Arc-Bio, EdenRoc, OvaScience, Cohbar, Selphagy, Senolytic Therapeutics, and Animal Biosciences.
What we do: College students and postdoctoral fellows within the lab can select to study a wide range of methods, together with bioinformatics, molecular biology, epigenetic reprogramming, and animal physiology. We aren’t motivated by any particular approach however as an alternative select to begin with scientific questions that if answered would enhance lives and make the world a greater place. Research within the lab embrace the evaluation of DNA restore, fertility, mitochondrial dysfunction, wound therapeutic, cardiac failure, muscle loss, the interactions between epigenetic and genetic instability, and dementia, and entire physique and tissue reprogramming. Strategies embrace mouse physiology and cognition, molecular biology, medicinal chemistry, high-throughput molecule screening, software program design, and genomics. We even have a Particular Tasks Division that works on different areas of biology apart from getting old that would make a giant distinction in folks’s lives corresponding to detection of infectious illnesses by genomics and cleansing enzymes for enhancing biosecurity.
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